Antibacterial Potential and Phytochemical Analysis of Momordica foetida Extracts: A Prospective Study

Okiring Emmanuel Omieke

Department of Pharmacy, Kampala International University, Uganda

ABSTRACT

Momordica foetida, a medicinal plant from the Cucurbitaceae family, has been traditionally used across tropical Africa for its therapeutic properties. This study aimed to evaluate the antibacterial effects of extracts from different parts of Momordica foetida (leaves, stems, and fruits) against common bacterial pathogens and analyze their phytochemical composition. The extraction process involved cold water, hot water, and ethanol methods. Antibiotic susceptibility testing and minimum inhibitory concentration (MIC) assays were conducted against Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Klebsiella pneumoniae. Phytochemical screening was performed to identify the presence of alkaloids, tannins, flavonoids, quinolones, terpenoids, and saponins. Results showed significant antibacterial activity of ethanol stem extract against Staphylococcus aureus. Phytochemical analysis revealed the presence of various bioactive compounds across all extracts. The findings suggest the potential of Momordica foetida as a source of antibacterial agents, particularly against Staphylococcus aureus infections.

Keywords: Phytochemical Analysis; Momordica foetida; Antibacterial Activity; Wound Infections; Anti-bacterial agents

CITE AS: Okiring Emmanuel Omieke (2024). Antibacterial Potential and Phytochemical Analysis of Momordica foetida Extracts: A Prospective Study. IDOSR JOURNAL OF BIOCHEMISTRY, BIOTECHNOLOGY AND ALLIED FIELDS 9(2):7-14. https://doi.org/10.59298/IDOSR/JBBAF/24/92.7140000