Managing Off-Label Use of Steroids: Ethical and Legal Guidelines for Practitioners

Bizimana Rukundo T.

Faculty of Biological Sciences Kampala International University Uganda

ABSTRACT

Off-label steroid use in clinical practice raises significant ethical, legal, and safety challenges, particularly in areas like rheumatology, sports medicine, and dermatology. While such use may offer therapeutic benefits in conditions beyond approved indications, it also poses risks related to patient safety, informed consent, misuse, and potential legal consequences. This review explores the complexities surrounding off-label steroid prescriptions, including the regulatory frameworks that govern their use, the ethical considerations involved, and the responsibilities of healthcare practitioners in ensuring patient safety. By examining best practices, clinical guidelines, and case studies, the review provides a comprehensive framework for responsible prescribing, emphasizing the need for clear protocols, enhanced monitoring, and education for both practitioners and patients. Ultimately, it calls for improved regulations and a more ethical approach to the off-label use of steroids to ensure patient protection and prevent misuse.

Keywords: Off-label use, steroids, ethical prescribing, informed consent, patient safety.

CITE AS: Bizimana Rukundo T.(2025). Managing Off-Label Use of Steroids: Ethical and Legal Guidelines for Practitioners. IDOSR JOURNAL OF SCIENTIFIC RESEARCH 10(1):49-53. https://doi.org/10.59298/IDOSRJSR/2024/10.1.49530